A proximity-dependent surface hybridization strategy for constructing an efficient signal-on electrochemical DNAzyme sensing system.
نویسندگان
چکیده
A proximity-dependent surface hybridization strategy is employed for designing a "signal-on" electrochemical DNAzyme biosensor. By taking advantage of the high sensitivity of the PDSH strategy, and by realizing the enzymatic hydrolysis reaction in a homogenous system with a unimolecular design, the proposed biosensor shows a very high sensitivity to target molecules.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 76 شماره
صفحات -
تاریخ انتشار 2012